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Hidden Link Between Artificial Sweeteners and Chronic Pain

October 28, 2025

If you are living with chronic back or neck pain, you've probably tested everything—stretches, heating pads, over-the-counter medications. But have you thought about the impact your diet drinks and “sugar-free” snacks may have? Developing research suggests that artificial sweeteners might be impairing your pain relief efforts through an unexpected pathway: your gut. Minster Chiropractic Center is here to explore any potential avenues to help you get your pain under control!

THE GUT-PAIN CONNECTION

Your gut isn't just responsible for digestion—it's home to trillions of microorganisms that influence inflammation throughout your entire body, including your spine and neck. Recent groundbreaking research has revealed a direct link between artificial sweeteners, gut health, and chronic pain sensitivity.

A 2025 Mendelian randomization study by Zhao and colleagues demonstrated that artificially sweetened foods can essentially cause chronic pain by disturbing the gut microbiota. (1) This isn't just correlation—the research shows a causal relationship between consuming these sweeteners and increased pain levels.

HOW SWEETNERS TRIGGER PAIN

Artificial sweeteners can change the balance of beneficial bacteria living in your digestive system. These disturbed microbes trigger inflammatory responses that go throughout your body. Research released in the British Journal of Anaesthesia by Guo and colleagues depicts how that gut bacteria impact pain levels by altering immune responses and how sensitive your nerves become. (2)

For back and neck pain sufferers seeking help at Minster Chiropractic Center, this inflammation can raise pain sensitivity in already susceptible areas. Your spinal nerves become more reactive, making existing discomfort worse and potentially slowing your recovery.

TAKING ACTION

Before you see us again, consider removing artificial sweeteners from your diet. This would involve checking labels on diet sodas, protein bars, yogurts, and sugar-free desserts for ingredients like aspartame, sucralose, and saccharin

Chiropractic physicians understand that pain management demands a whole-body approach. While spinal adjustments address mechanical dysfunction, decreasing inflammation through dietary modifications can significantly raise treatment outcomes. By sustaining your gut health, you're creating an internal environment more conducive to healing and less open to pain signals. Little dietary changes might be a great extra to your pain relief strategy with Minster Chiropractic Center.

Your path to back pain relief and/or neck pain relief may begin with what you take out of your grocery cart.

CONTACT Minster Chiropractic Center

Listen to this PODCAST with Dr. James Cox, on The Back Doctors Podcast with Dr. Michael Johnson as he illustrates the impact inflammation has on the immune system and the help chiropractic care like The Cox® Technic System of Spinal Pain Management that Minster chiropractic patients may experience.

Schedule your Minster chiropractic appointment soon.